Spontaneous Breathing Non-Intubated Bronchoscopy
Conditions
Interventions
Oliceridine Group (O Group):In the Oliceridine group (O group),
patients received intravenous slow administration of oliceridine at 0.02 mg/kg.
Propofol (1.5–2.5 mg/kg) was administered according t
Sufentanil Group (S Group):In the control group (S group), oliceridine was replaced with an intravenous bolus of sufentanil at 0.1 µg/kg, while all other procedures remained identical to the O group.
Sponsors
Xiangshan Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Age 18–64 years; 2. ASA classification I–III; 3. BMI 18.5–28.0 kg/m²; 4. Voluntary participation & signed informed consent 5. Able to cooperate with medical personnel.
Exclusion criteria
Exclusion criteria: 1. Allergy or contraindications to study drugs; 2. Uncontrolled diabetes, hypertension, or anemia; 3. Contraindications to general anesthesia; 4. Severe cardiovascular, cerebrovascular, or respiratory diseases; 5.Pregnancy or breastfeeding; 6. Long-term opioid or benzodiazepine use; 7. Severe vertigo.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Respiratory-Related Adverse Events (RAEs); | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Oxygen Saturation (SpO?);Patient Satisfaction;Onset Time of Anesthesia;Pain Rating;Blood Pressure;Anesthetic dosage;Surgical operation time;anesthesia recovery time;Time of Discharge from the PACU; | — |
Countries
China
Contacts
Public ContactYang Cao
Xiangshan Hospital of Wenzhou Medical University
Outcome results
None listed