Knee arthropathy
Conditions
Interventions
Control group:Administer 10-13mg of ropivacaine at room temperature during subarachnoid anesthesia.
Experimental group:During subarachnoid anesthesia, 10-13 mg of warmed ropivacaine (at 37?) is administered.
Sponsors
Affiliated Hospital of Yan'an University
Eligibility
Sex/Gender
All
Age
No minimum to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age<=75 years; 2.ASA II~III level; 3.18kg/m^2<=BMI<=30kg/m^2; 4. Unilateral knee replacement surgery; 5. Neuraxial anesthesia is planned.
Exclusion criteria
Exclusion criteria: 1. Inability to take care of oneself before surgery; 2. History of delirium before surgery; 3. Combined with mental illness such as dementia; 4. Preoperative albumin =10 mmol/L; 7. Poorly controlled hypertension; Preoperative blood pressure >=140/90; 8. Deep vein thrombosis before surgery; 9. Preoperative fractures in other parts; 10. Refusal to sign the study informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The distance walked during the 6-minute walk test (6MW) when the patient takes the first ambulation out of bed after the operation.;The early ambulation rate of patients in this group was significantly higher than that in the control group.(.); | — |
Secondary
| Measure | Time frame |
|---|---|
| Onset time of sensory nerve block;The highest block level;Whether epidural supplementation is carried out during the operation and the dosage of the supplementary drug;The incidence of intraoperative hypotension;The satisfaction degree of surgeons with muscle relaxation during the operation;Muscle strength rating upon arrival at the PACU after the end of the operation;The catheterization rate;The flexion degree of the knee joint at 6h, 12h, 24h and 48h after the operation.;The time of the first ambulation after surgery;The incidence of postoperative nausea and vomiting;The incidence of postoperative orthostatic hypotension;VAS scores at rest and during movement at 12 hours, 24 hours and 48 hours after surgery;The effective pressing times of PCIA within 24 hours after surgery and the total amount of opioids used within 24 hours after surgery;The occurrence of postoperative complications (delirium, cardiovascular complications, pulmonary complications, lower extremity deep vein thrombosis).;The time of the first drinking and eating after surgery.;The length of postoperative hospital stay;At 30 days after surgery, the Visual Analogue Scale (VAS) and Lower Extremity Functional Scale (LEFS) were used to evaluate the pain intensity and functional ability; | — |
Countries
China
Contacts
Public ContactZhang Erfei
Affiliated Hospital of Yan'an University
Outcome results
None listed