sarcopenia
Conditions
Interventions
Intervention group:Arginine+fish oil
Control group:placebo
Cross section (diabetes group):none
Sponsors
The 925th Hospital of the Chinese Joint Logistics Support Force
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: Cross-sectional study inclusion criteria: 1. over 60 years old, agreed to participate in the survey and signed informed consent; 2. Patients with diagnosed type 2 diabetes; 3. Can independently complete the body composition analysis and physical function test; Inclusion criteria for intervention research: 1. Over 60 years old, agree to participate in the survey and sign the informed consent; 2. Diagnosed patients with type 2 diabetes combined with sarcopenia; 3. Those who can eat orally and tolerate enteral nutrition; 4. can independently complete the body composition analysis and physical function test;
Exclusion criteria
Exclusion criteria: Exclusion criteria for cross-sectional studies: 1. Serious cognitive impairment, mental illness, etc., resulting in inability to participate in the test normally; 2. Patients with heart disease (including those equipped with pacemakers, heart stents), implant artificial joints, etc., who cannot participate in body composition tests and physical indicators tests; 3. Patients with severe dysfunction of heart, liver, kidney and other organs; 4. Refusing to cooperate with investigators. Exclusion criteria for intervention study: ? Patients with severe cognitive impairment or mental illness who could not normally participate in the test; ? Patients with heart disease (including those equipped with pacemakers, heart stents), implant artificial joints, etc., who cannot participate in body composition tests and physical indicators tests; ? Patients with severe dysfunction of heart, liver, kidney and other organs; ? Patients with dysphagia; ?Long-term use of thyroid drugs, steroids and estrogen and other drugs; ? Poor compliance and study doctors deemed unsuitable candidates; ? Patients with severe sepsis or systemic inflammatory response syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6m pace;Serum insulin;Triglyceride-glucose index;SMI;Calf circumference;grip;glut4 glucose transporter;NO;Fasting blood glucose;2h postprandial blood glucose;HOMA-IR;SARC-CALF; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of hospitalization;Number of readmissions within one year; | — |
Countries
China
Contacts
Public ContactYuan Lijia
The 925th Hospital
Outcome results
None listed