Endometrial disease
Conditions
Interventions
0.3mg/kg ketamine+2-2.5mg/kg propofol :0.3mg/kg ketamine+2-2.5mg/kg propofol anesthesia induction. When sufficient sedation is achieved [MOAA/S score = 1], a laryngeal mask is inserted, followed by hy
0.4mg/kg ketamine+2-2.5mg/kg propofol :0.4mg/kg ketamine+2-2.5mg/kg propofol anesthesia induction. When sufficient sedation is achieved [MOAA/S score = 1], a laryngeal mask is inserted, followed by hy
0.5mg/kg ketamine+2-2.5mg/kg propofol :0.5mg/kg ketamine+2-2.5mg/kg propofol anesthesia induction. When sufficient sedation is achieved [MOAA/S score = 1], a laryngeal mask is inserted, followed by hy
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1.All patients who require painless hysteroscopy for diagnosis and treatment and are willing to undergo it; 2.ASA levels 1-3; 3.The patient has good treatment compliance; 4.Mentally normal, able to communicate normally; 5.Clear understanding, voluntary participation in research, and signing of informed consent form; 6.18<=BMI<=30kg/m^2.
Exclusion criteria
Exclusion criteria: There are contraindications to esketamine, such as hyperthyroidism, glaucoma, and macroangioma, hypertension is poorly controlled or untreated (systolic/diastolic blood pressure exceeds 180/100mmHg at rest, and severe cardiopulmonary, liver or kidney dysfunction, diabetes, and other metabolic diseases, long-term hormone use, drug or alcohol abuse history, or mental illness. Patients receiving emergency surgery and those who are allergic to active ingredients or excipients of drugs in this study are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypotension incidence rate;Incidence of bradycardia;Anesthesia induction duration;Wake up duration;Duration of stay in the recovery room;Induced additional drug frequency;Maintain the frequency of additional medication;Intraoperative and postoperative adverse events;Patient satisfaction;Postoperative anxiety and sleep status; | — |
Countries
China
Contacts
Public ContactXuan Zhao
Shanghai Tenth People's Hospital
Outcome results
None listed