Diabetic Peri-implantitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. Informed consent and signing of relevant instruments by the patient; 3. Single implant;
Exclusion criteria
Exclusion criteria: 1. Age <18 years; 2. Patient refuses to participate in the trial/signs the relevant informed consent form; 3. Suffering from a systemic disease other than diabetes mellitus that has an effect on the implant; 4. Use of medications with peri-implant effects within the last 6 months; 5. Having other inflammatory diseases in the oral cavity other than peri-implantitis and in the acute stage; 6. Pregnancy/nursing period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood levels of zinc and iron ions;Zinc and iron ions in gingival sulcus fluid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Peri-implant plaque index with peri-implantitis;Gingival index of implants with peri-implantitis;Implant bleeding on probing with peri-implantitis;Depth of peri-implant probing with peri-implantitis;Implant mobility with peri-implantitis;Diagnostic imaging of alveolar bone loss with peri-implantitis;Glycosylated hemoglobin level in fasting blood;Fasting blood levels of superoxide dismutase;Indicators of oxidative stress in the gingival sulcus;Inflammatory correlates of gingival sulcus fluid;Gingival fluid osteoclast-related factor protein; | — |
Countries
China
Contacts
West China Hospital of Stomatology, Sichuan University