Postoperative diaphragmatic dysfunction
Conditions
Interventions
Experimental group:Patients were administered with continuous intravenous lidocaine infusion from the start of anesthesia induction to 24 hours postoperatively, starting with intravenous lidocaine 1.5
Control group:The same volume of 0.9% normal saline was administered at the same infusion rate
Sponsors
The First People's Hospital of Foshan
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients undergoing elective laparoscopic colorectal cancer surgery: 1.Age 45-80 years; 2.ASA Grading I-III; 3.Body mass index BMI <=30 kg /m^2; 4.Patients and their families voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Preoperative diaphragm-related diseases or neuromuscular related diseases; 2.History of previous thoracic and abdominal trauma and surgery; 3.Preoperative combined with severe cardiovascular, liver parenchymal damage (ALT or AST >2 times the normal value), renal failure (SCr>177 umol/L), respiratory failure; 4.Lidocaine allergy; 5.History of epilepsy; 6.Mental and psychological diseases, cognitive dysfunction; 7.Patient or family member refuses this study or refuses to undergo diaphragm or lung ultrasound.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative diaphragmatic dysfunction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diaphragmatic excursion;Pulmonary complications (including pulmonary infection, respiratory failure, atelectasis, pneumothorax, pleural effusion, bronchospasm, and aspiration pneumonia) within 7 days after surgery;Diaphragmatic thickening fraction ;Diaphragmatic rapid shallow breathing index;Diaphragmatic contraction velocity; | — |
Countries
China
Contacts
Public ContactWanyou He
The First People's Hospital of Foshan
Outcome results
None listed