Vertebroplasty
Conditions
Interventions
Experimental group:Sufentanil citrate injection 0.1µg/kg and Remazolam toluenesulfonate 0.2mg/ kg were injected intravenously before the operation. Remazolam toluenesulfonate was injected intravenousl
Control group:Sufentanil citrate injection 0.1µg/kg was injected intravenously before the operation, 0.9% sodium chloride injection of the same ml was injected intravenously in the experimental group,
Sponsors
Jintang County first People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Age 60-90 years old, BMI (18.5-30kg/m^2); (2) Elective vertebroplasty surgery, anesthesia method: local infiltration anesthesia; (3) Clear, no mental disorder, intellectual disability and other diseases; (4) ASA classification: I-III. grades; Cardiac function: Grades 1-3.
Exclusion criteria
Exclusion criteria: (1) Combined with heart, lung and other vital organ failure; (2) Combined with acute and chronic systemic infection; (3) Those with a history of long-term antipsychotic medication, severe depression, and myasthenia gravis; (4) Allergy to the drugs used in this study; (5) Patients who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean blood pressure;Heart rate;Pulse oxygen saturation;RASS sedative agitation score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative hypotension;Incidence of respiratory depression;Incidence of severe bradycardia(< 50 times /min);Incidence of low oxygen saturation (SpO2 < 90%); | — |
Countries
China
Contacts
Public ContactQu Yang
Jintang County first People's Hospital
Outcome results
None listed