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The influence of endoscopic treatment timing on the prognosis of cirrhosis patients with acute esophageal variceal bleeding

The influence of endoscopic treatment timing on the prognosis of cirrhosis patients with acute esophageal variceal bleeding

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099205
Enrollment
Unknown
Registered
2025-03-19
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute esophagogastric variceal bleeding in cirrhosis

Interventions

Early Endoscopy Group:Endoscopy performed within 24 h
Delayed Endoscopy Group:endoscopy performed over 24 h

Sponsors

The 960th hospital of the Joint Logistics Support Force of the People’s Liberation Army
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.Liver cirrhosis with acute bleeding from esophageal and gastric varices: The patient vomited blood and had black stools within 120 hours before being hospitalized. 2.Endoscopic examination confirmed that the bleeding originated from esophageal or gastric varices. 3.The interval between the patient’s last episode of vomiting blood and having black stools and the endoscopic treatment was less than 5 days. 4.The patient is 18 years old or older.

Exclusion criteria

Exclusion criteria: 1.Patients who have not undergone an endoscopy or have medical conditions that prohibit endoscopy. 2.Individuals who received endoscopic treatment at a different hospital within 5 days prior to admission. 3.Those with severe dysfunction of organs other than the liver, such as heart failure, lung diseases, or terminal cancers other than hepatocellular carcinoma. 4.Pregnant women or those who are breastfeeding. 5.Patients with incomplete medical records, missing endoscopy reports or laboratory data, or those who were lost to follow-up during the observational period.

Design outcomes

Primary

MeasureTime frame
Rebleeding incidence rate;In-hospital mortality rate;Postoperative fever incidence rate ;6-week mortality rate;Length of hospital stay;Hospitalization cost;

Countries

China

Contacts

Public ContactXinhui Li

The 960th hospital of the Joint Logistics Support Force of the People’s Liberation Army

muzixh00@163.com+86 152 6341 2617

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026