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Effect of Ultrasound-Guided Femoral Nerve Block Combined with Peri-Femoral Artery Block on the Incidence of Tourniquet-Induced Hypertension in Knee Arthroplasty: A Randomized Controlled Trial.

Effect of Ultrasound-Guided Femoral Nerve Block Combined with Peri-Femoral Artery Block on the Incidence of Tourniquet-Induced Hypertension in Knee Arthroplasty: A Randomized Controlled Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099191
Enrollment
Unknown
Registered
2025-03-19
Start date
2025-03-20
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Femoral nerve block group.:Femoral nerve block group on the operative side.
Femoral nerve + peri-femoral artery block group.:Femoral nerve + peri-femoral artery blockon the operative side.

Sponsors

Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged between 18 and 70 years old. 2. American Society of Anesthesiologists (ASA) physical status I to II. 3. Patients undergoing elective knee arthroplasty under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Allergic to local anesthetics. 2. Contraindications to tourniquet use (infection at the block site, peripheral neuropathy, peripheral vascular disease, previous arterial bypass grafting). 3. Patients with ischemic heart disease or poorly controlled hypertension recently. 4. Tourniquet use time less than 45 minutes or more than 120 minutes. 5. Those who are unwilling to participate in the trial.

Design outcomes

Primary

MeasureTime frame
The incidence of tourniquet-induced hypertension during surgery.;

Secondary

MeasureTime frame
Mean arterial pressure (MAP), systolic blood pressure (SBP), and heart rate (HR) were measured at the following time points: before anesthesia (T0), 1 minute before tourniquet inflation (T1), and at 15-minute intervals after tourniquet inflation (15 [T2], 30 [T3], 45 [T4], 60 [T5], 75 [T6], and 90 minutes [T7]);The consumption of urapidil;The consumption of remifentanil;Postoperative Visual Analogue Scale (VAS) score;Postoperative quality of recovery score;

Countries

China

Contacts

Public ContactJia Mengxing

Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University

xzmu_jiamengxing@163.com+86 158 9523 8016

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026