Epilepsy
Conditions
Interventions
intractable epilepsy patient group:none
Healthy control group:none
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
14 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients who meet the diagnostic criteria for epilepsy according to the ILAE-2017, and who have not achieved seizure freedom despite correctly using two or more tolerable antiepileptic drugs at sufficient doses and durations of therapy. The duration without seizures should be three times the longest seizure-free interval before treatment or one year (whichever is longer).
Exclusion criteria
Exclusion criteria: 1. age >65 or <14 years old 2. history of other serious systemic or neuro-psychological diseases 3. history of substance or alcohol abuse 4. not signed an informed consent form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| three-dimensional T1-weighted imaging;three-dimensional T2-weighted imaging;Diffusion weighted imaging (DWI);resting state functional magnetic resonance imaging (fMRI);task functional magnetic resonance imaging (fMRI);Quantitative susceptibility mapping (QSM); | — |
Countries
China
Contacts
Public ContactPing Jiang
West China Hospital of Sichuan University
Outcome results
None listed