Rectal cancer
Conditions
Interventions
Experimental group:EN was initiated on the first postoperative day and SPN was received for at least 5 days until 80% of the energy target was achieved through EN or until discharge. EN products are r
Control group:EN was initiated on the first postoperative day and SPN was received for at least 5 days until 80% of the energy target was achieved through EN or until discharge. Postoperative enteral
Sponsors
The First Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients with pathologically confirmed colorectal cancer undergoing surgery; 2. Age >=60 years old, male or female; 3. Have not received any anti-tumor treatment for rectal cancer, including radiotherapy, chemotherapy, surgery, etc. 4. ECOG PS 0-1; 5. Normal function of major organs; 6. Signed written informed consent and volunteered to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Preoperative nutritional support with ?-3PUFA; 2. Preoperative parenteral nutrition; 3. Infection existed before surgery; 4. Abnormal liver function; 5. Renal dysfunction; 6. Unstable vital signs or hemodynamic parameters; 7. Systemic lupus erythematosus; 8. Type I diabetes mellitus; 9. Hyperthyroidism; 10.Have participated in other clinical research; 11. According to the investigator's judgment, there are other factors that may lead to the forced termination of the study, such as other serious diseases (including mental diseases) requiring combined treatment, alcohol abuse, drug abuse, family or social factors, and factors that may affect the safety or compliance of the subjects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary infection;Intestinal infection;Urinary tract infection;Incision infection;Interleukin-6; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine test markers;C-reactive protein;Procalcitonin;Liver function;Renal function;Lipid ;T lymphocyte subsets in peripheral blood;Fecal microbiota;Quality of life score within 1 month after surgery;Mortality within 3 months after surgery; | — |
Countries
China
Contacts
Public ContactJianping Zhou
The First Hospital of China Medical University
Outcome results
None listed