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Risk factor analysis and predictive model construction for the prognosis of acute liver injury in sepsis

Risk factor analysis and predictive model construction for the prognosis of acute liver injury in sepsis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500099170
Enrollment
Unknown
Registered
2025-03-19
Start date
2024-01-07
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute liver injury in sepsis

Interventions

Acute liver injury group:N/A
Non-acute liver injury group:N/A

Sponsors

Hai'an People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Diagnosed as sepsis (sepsis 3.0); 2. Age >= 18 years old; 3. First time entering the ICU.

Exclusion criteria

Exclusion criteria: 1. Lack of ALT or AST laboratory indicators makes it difficult to diagnose sepsis; 2. Previous liver diseases with acute liver injury (acute and chronic hepatitis; liver abscess; cholecystitis; biliary obstruction; malignant tumors of the bile duct and liver; cirrhosis; liver transplantation); 3. Acute myocardial infarction.

Design outcomes

Primary

MeasureTime frame
Alanine aminotransferase;Aspartate aminotransferase;Bilirubin;28 day prognosis;—

Secondary

MeasureTime frame
acute physiology and chronic health evaluation scoring systemII;Sequential Organ Failure Assessment;Duration of stay in ICU;alkaline phosphatase;White blood cell count;platelet count;creatinine;Urea nitrogen;lactic acid;—

Countries

China

Contacts

Public ContactWei Zhang

Hai'an People's Hospital

775916113@qq.com+86 159 6289 9899

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026