nasosinusitis
Conditions
Interventions
Ciprofol Group:0.4 mg/kg was induced with ciprofol, and ciprofol pump at a constant rate, with an initial dose of 0.8 mg/kg/h and a range of 0.4~2.4 mg/(kg·h).
Propofol group:Propofol was used to induce 2 mg/kg,and propofol was used to pump at a constant rate, with an initial dose of 6.0 mg/(kg·h) and a range of 4~12 mg/(kg·h).
Sponsors
Affiliated Hospital of Guizhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective nasal endoscopic surgery 2. Gender is not limited, age >= 18 years old and <= 65 years old; 3. American Society of Anesthesiologists (ASA) Class I or II; 4. 18kg/m^2<= BMI <=30kg/m^2; 5. Inform the patient and his family of the anesthesia plan and risks, and the patient agrees to anesthesia and signs the informed consent form for clinical trials.
Exclusion criteria
Exclusion criteria: 1. Patients with hypertension (uncontrolled hypertension or SBP>160mmHg and/or DBP>100mmHg after treatment with antihypertensive drugs 2. Those who have a history of allergy to anesthetic drugs (benzodiazepines, propofol, etc.) and have contraindications to general anesthesia; 3. Inform the anesthesia plan and risks, and patients who cannot be accepted for controlled blood pressure; 4. Those who have mental and nervous system diseases and are unable to think independently and communicate normally; 5. Those with a history of drug abuse, alcoholism, and long-term use of sedatives, pain relievers, and sleeping pills; 6. Patients who have undergone nasal endoscopic surgery in the past 3 months; 7. other reasons could not be included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of controlled hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Field quality score;Hemodynamic index at different time points (heart rate,non-invasive blood pressure, saturation of pulse oximetry);Dosage of anesthetic drugs;Operation duration;Duration of anesthesia;awakening time;extubation time;Time to target blood pressure; | — |
Countries
China
Contacts
Public ContactChen Mi
Affiliated Hospital of Guizhou Medical University
Outcome results
None listed