pigmentation
Conditions
Interventions
Vitamin C group :Subjects in the income group began taking oral medication on the day after undergoing photoelectric therapy. According to the randomization results, the VC group took 3 vitamin C tabl
Vitamin C + Vitamin E group :Subjects in the income group began taking oral medications on the day following photoelectric therapy, according to the randomized grouping results. The VC+VE group was i
blank group:Subjects in the income group began taking oral medication on the day after undergoing photoelectric therapy, according to the randomized grouping results. The control group did not take or
Sponsors
The Second Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 60 years old; 2. Confirmed as freckles, with spots on both sides of the face; 3. With or without melasma; 4. Preparing to use the Cynergy Medlite-C6 laser device for freckle removal; 5. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Suffering from mental illness; 3. People with diseases that are advised to be cautious when using vitamin C and vitamin E: cystinuria, gout, hyperoxaluria, oxalate deposition disease, urate kidney stones, diabetes, glucose-6-phosphate dehydrogenase deficiency, hemochromatosis, sickle cell anemia, iron deficiency anemia. 4. Individuals allergic to vitamin C and vitamin E 5. Subjects with skin diseases that may affect the assessment of treatment efficacy in the treatment area, such as extensive scarring or skin diseases, a history of skin tumors, or the presence of extensive active inflammation and/or unhealed wounds; 6. Patients with photosensitive diseases and those who have been exposed to sunlight within the past month; 7. Using topical medications (such as hydroquinone, levo-vitamin C, etc.) or oral medications (such as contraceptives, corticosteroids, isotretinoin, etc.) that may affect pigmentation within one month before and after laser treatment. 8. Any treatment that may affect pigmentation (such as acid, intense pulsed light, etc.) within 1 month before and after laser treatment 9. Participated in other clinical studies within the past month; 10. Subjects whom the researcher deems unsuitable for participation in this clinical study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hyperpigmentation Area and Severity Index; | — |
Countries
China
Contacts
Public ContactYangyan Yi
The Second Affiliated Hospital of Nanchang University
Outcome results
None listed