Hip joint disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age greater than 60 years old and less than 80 years old; 2.ASA I~III level; 3.18kg/m^2<=BMI<=30kg/m^2; 4. Estimated operation time < 2.5 hours; 5. Emergency or elective hip replacement surgery; 6. Neuraxial anesthesia is planned.
Exclusion criteria
Exclusion criteria: 1. Inability to take care of oneself before surgery; 2. History of delirium before surgery; 3. Combined with mental illness such as dementia; 4. Preoperative albumin =10mmol/L; 7. Poorly controlled hypertension: preoperative blood pressure >=140/90mmHg/L; 8. Deep vein thrombosis before surgery; 9. Preoperative fractures in other parts; 10. FRAIL Frailty Scale score>=3 points; 11. Refusal to sign the study informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative Epidural Drug Administration Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative Hypotension Incidence;Types and Doses of Vasoactive Drugs Used Intraoperatively;Intraoperative Surgeon’s Muscle Relaxation Satisfaction;Intraoperative output;Intraoperative fluid replacement volume and type;Intraoperative incidence of nausea and vomiting;Postoperative incidence of hypotension;Postoperative orthostatic hypotension;Postoperative incidence of nausea and vomiting;Time to first water intake and food intake after surgery;Rate of urinary catheter retention;Time to first ambulation after surgery;Resting and movement VAS scores at 4h, 12h, 24h, and 48h after surgery;Number of effective presses of PCA (Patient-Controlled Analgesia) within 48 hours after surgery;Total amount of opioid analgesics used within 48 hours after surgery;Types and doses of analgesic drugs administered in the ward after surgery;Occurrence of postoperative complications (delirium, cardiovascular complications, pulmonary complications, deep vein thrombosis of the lower limbs);Postoperative hospital stay duration;Pharmacoeconomic evaluation; | — |
Countries
China
Contacts
Affiliated Hospital of Yan'an University