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Research on the Application of Ultrasonic Cavitation in Systemic Treatment of Advanced Liver Cancer

Research on the Application of Ultrasonic Cavitation in Systemic Treatment of Advanced Liver Cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500099130
Enrollment
Unknown
Registered
2025-03-19
Start date
2023-11-19
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver cancer

Interventions

Cavitation treatment group:None
Control group:None

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18~75 years old; 2. Measurable and evaluable tumor lesions on images; 3. Patients who have been clinically recognized as feasible with transarterial intervention combined with target immunity; 4. No serious damage to liver, heart, brain, kidneys and other important organs 5. Physical condition is <=2 with ECOG (Eastern Cooperative Oncology Group) score; 6. Sign the informed consent form and have good compliance, with complete medical records and imaging data.

Exclusion criteria

Exclusion criteria: 1. Combined with organic changes of important organs such as heart, brain, kidney, etc., or accompanied by other malignant tumors; 2. Allergy to chemotherapy drugs or ultrasound contrast media and hypersensitivity; 3. Patients with incomplete clinical data and imaging data; 4. Patients with poor follow-up compliance.

Design outcomes

Primary

MeasureTime frame
2-year objective response rate ORR between treatment and control groups;

Secondary

MeasureTime frame
Overall Survival OS;Contrast-enhanced ultrasound parameters;Serum tumor marker;Adverse reaction;Disease control rate DCR;Duration of response DOR;Objective response rate (ORR).;Progression-free survival PFS;

Countries

China

Contacts

Public ContactXu Xiaohong

Affiliated Hospital of Guangdong Medical University

13828297586@139.com+86 138 2829 7586

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026