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Effects of oral carbohydrates before and early after surgery on the quality of recovery after general anesthesia: a randomized controlled trial

Effects of oral carbohydrates before and early after surgery on the quality of recovery after general anesthesia: a randomized controlled trial - Effects of oral carbohydrates before and early after surgery on the quality of recovery after general anesthesia: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099119
Enrollment
Unknown
Registered
2025-03-18
Start date
2025-03-20
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases of various types of surgical systems

Interventions

A:8 hours of preoperative water fasting + 2 hours of preoperative non-intake of 12.5% carbohydrates + water fasting in the wake room
B:8 hours of preoperative fasting of water + 2 hours of oral administration of 12.5% carbohydrate 200ml + water continence in the wake room + resumption of drinking water 6 hours after surgery
C:8 hours of preoperative fasting of water + 2 hours of no intake of 12.5% carbohydrate before surgery + oral administration of 200ml of 12.5% carbohydrate in the postoperative recovery room + resumpt
D:8 hours of preoperative fasting water + 2 hours of oral administration of 12.5% carbohydrate 200ml + oral administration of 12.5% carbohydrate 200ml in the postoperative recovery room + resumption o

Sponsors

Zhongshan Hospital Affiliated to Fudan University Xiamen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18~75 years old 2.BMI: 18~30 kg/m2 3.ASA Grade ? or ? 4. Plan surgery with elective general anesthesia 5. Sign the informed consent to the research protocol

Exclusion criteria

Exclusion criteria: 1. Pregnant woman;2. Diabetes mellitus, hyperglycemia, hypoglycemia below 2.8mm/L 3.High risk of reflux aspiration (such as cardiac achardia, pyloric obstruction, digestive tract obstruction, etc.) 4.Previous history of gastrointestinal surgery or gastrointestinal surgery 5.recently taking drugs that affect gastrointestinal motility 6. Mental disorders can not cooperate 7. People with carbohydrate allergy 8.History of allergy 9. Gastrointestinal motility disorder, swallowing dysfunction 10. Renal insufficiency or failure 11. Preoperative ASA grade III or above

Design outcomes

Primary

MeasureTime frame
Quality of Recovery,QoR-15;Homeostasis Model Assessment for ß-cell function (HOMA-ß);

Secondary

MeasureTime frame
Subjective comfort:Hunger, Thirst, Anxiety;HOMA-IR(homeostasis model assessment-insulin resistance),;Incidence of postoperative nausea and vomiting;QUICKI(quantitative insulinsensitivitycheck index);

Countries

China

Contacts

Public ContactLiang Chao

Zhongshan Hospital,Fudan University(Xiamen Branch)

Superwm226@126.com+86 159 2167 9955

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026