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The optimal programmed intermittent epidural bolus volume with the dural puncture epidural technique for labour analgesia in pregnant women with gestational hypertension : a coin of biased up-and-down sequential allocation study

The optimal programmed intermittent epidural bolus volume with the dural puncture epidural technique for labour analgesia in pregnant women with gestational hypertension : a coin of biased up-and-down sequential allocation study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099107
Enrollment
Unknown
Registered
2025-03-18
Start date
2025-03-20
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational hypertension

Interventions

Experimental group:The pulse volume group allocated to each parturient was determined by statistical experts through programming based on the Biased Coin Up-Down Sequential Method and the response of

Sponsors

The Fourth Hospital of Shijiazhuang
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
22 Years to 40 Years

Inclusion criteria

Inclusion criteria: In this study, the first-time women with gestational hypertension who underwent labor analgesia were selected, aged 23~40 years old, with a BMI of <=35kg/m^2 and ASA grade II.

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to local anesthetics or opioids; 2. Those who take analgesics 4 hours before delivery; 3. Patients with other acute and chronic infections; 4. Those with autoimmune system diseases, blood system diseases, and mental system diseases; 5. Platelet count less than 100?109/L or neuraxial anesthesia contraindications.

Design outcomes

Primary

MeasureTime frame
Effective analgesia;

Secondary

MeasureTime frame
The highest sensory block plane;Modified Bromage scale score;Mean arterial pressure;Timing of the first and second stages of labor;Apgar score at 1 min and 5 min after birth;Umbilical artery blood gas analysis immediately after delivery of the fetus;Occurrence of adverse events;

Countries

China

Contacts

Public ContactZhang Binghui

The Fourth Hospital of Shijiazhuang

452706419@qq.com+86 131 8049 1860

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026