Acute brain injury
Conditions
Interventions
Esophageal manometry group (Group E):Esophageal balloon catheter for measuring esophageal pressure
Routine Settings Group (Group C):None
Sponsors
First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients who require emergency craniotomy due to acute brain injury, aged 18-75 years; 2. ASA rating >=3; 3. No history of lung surgery and other respiratory diseases before surgery; 4. No heart, liver, kidney and other serious systemic diseases or poor control of chronic diseases; 5. Sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1. History of esophageal reflux or esophageal ulcer, esophageal varices, and upper gastrointestinal surgery; 2. Severe liver and kidney dysfunction; 3. Preoperative circulatory decompensation, central circulatory failure; 4. Previous severe arrhythmia;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of pulmonary complications;Alveolar-arterial oxygen pressure difference (A-aDO2); | — |
Secondary
| Measure | Time frame |
|---|---|
| Arterial blood gas;Oxygenation index (PaO2/FiO2);Airway platform pressure; | — |
Countries
China
Contacts
Public ContactJuan Li
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed