Functional constipation in children
Conditions
Interventions
Control group:On the basis of basic treatment, lactulose oral solution is taken, the main ingredient of which is lactulose, the specification is 100ml: 66.7g). Manufacturer: Beijing Hanmi Pharmaceutic
Children aged 7-14 years should start with 10-15 ml and maintain 10-15 ml.
Standard dose group:On the basis of basic treatment, the standard dose group formula granules were taken, and the drug composition was Atractylodes macrocephalus, Pseudostellaria pseudostellaria, Ange
Children 7-14 years old take 1 sachet each time.
Reduced dose group:On the basis of basic treatment, the formula granules of the reduced group were taken, and the drug composition was Atractylodes macrocephalus, Pseudostellaria radix, Angelica sinen
Sponsors
Beijing Hepingli Hospital
Eligibility
Sex/Gender
All
Age
4 Years to 14 Years
Inclusion criteria
Inclusion criteria: Western medical diagnostic criteria: according to the Rome IV criteria, meet at least 2 of the following conditions, and occur at least once a week for at least 1 month: 1. No more than 2 bowel movements in the toilet per week, 2. Fecal incontinence at least once a week, 3. A history of fecal retention posture or excessive restraint of defecation, 4. A history of painful defecation or straining to defecate, 5. Large fecal masses in the rectum, 6. Coarse fecal masses that have blocked the toilet. 1. Meet the above Western medical diagnostic standards, and meet the TCM syndrome differentiation standards for spleen deficiency and intestinal dryness. 2. Those aged 4-14 years old and able to cooperate with taking drugs 3. Sign the informed consent form and volunteer to take the test
Exclusion criteria
Exclusion criteria: 1. History of gastrointestinal organic diseases or other major diseases 2. Persons > 14 years old or < 4 years old 3. Irritable bowel syndrome or constipation caused by medications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total number of spontaneous defecation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life scale score for patients with constipation;Bristol Stool Trait Scale score;Constipation Assessment Scale score;Constipation scoring system;Wexner constipation scoring system;Wexner rating;Blood routine test;Urine routine test;Shit routine test; | — |
Countries
China
Contacts
Public ContactYingke Liu
Beijing Hepingli Hospital
Outcome results
None listed