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Safety and efficacy of MateRegen® for endometrial repair after abortion: a prospective, multicenter, single-arm clinical study

Safety and efficacy of MateRegen® for endometrial repair after abortion: a prospective, multicenter, single-arm clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099033
Enrollment
Unknown
Registered
2025-03-18
Start date
2025-03-22
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical Abortion

Interventions

Experimental group:Cross-linked sodium hyaluronate gel

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Patients who have been examined and determined to undergo abortion (negative pressure suction); 2. Aged 18-45 years old; 3. Without serious systemic diseases. 4. Obtain informed consent to participate in the study; 5. Have good compliance and are willing and able to follow up after the operation as required; 6. Meet the following two criteria: (1) gestational week =1cm or the fetal bud is <3.0cm.

Exclusion criteria

Exclusion criteria: 1. Combination of other gynecologic diseases (e.g., history of uterine fibroids, adenomyosis, uterine adhesions); 2. Comorbidity with severe cardiac, hepatic, renal and other vital organ dysfunction; 3. Pre-existing menstrual disorders, polycystic ovary syndrome; 4. Hyaluronic acid allergy; 5. Other conditions that the investigator considers ineligible for enrollment.

Design outcomes

Primary

MeasureTime frame
Endometrial thickness;

Secondary

MeasureTime frame
Menstruation time;Duration of menstruation;Menstrual volume;Menstrual cramps;

Countries

China

Contacts

Public ContactJing Jiang

The Second Hospital of Hebei Medical University

jiangjing011@sina.com+86 137 8030 7399

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026