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Research on Early Quantitative Diagnosis and Precise Intervention of ICU-Acquired Weakness in Sepsis Based on High-Density Electromyography

Research on Early Quantitative Diagnosis and Precise Intervention of ICU-Acquired Weakness in Sepsis Based on High-Density Electromyography

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099024
Enrollment
Unknown
Registered
2025-03-17
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ICU-Acquired Weakness in Sepsis Based

Interventions

Standard treatment group :Began rehabilitation after diagnosis of ICU-AW based on MRC score (+).
Early rehabilitation group :Given rehabilitation immediately after hemodynamic stabilization.
HD-sEMG guided rehabilitation group :Group ii was given rehabilitation immediately after hemodynamic stabilization.

Sponsors

Tianjin People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients >18 years of age with sepsis within 24 hours of admission to MICU. The diagnostic criteria of sepsis refer to the International Consensus on the Definition of Sepsis and Septic Shock (the Third Edition), with sepsis= infection +SOFA>=2.

Exclusion criteria

Exclusion criteria: 1.The patient and his family members refused to participate in the study; 2.Patients with intracranial infection, intracranial space occupation, neuromuscular diseases, acute encephalopathy (trauma/hemorrhage/ischemia), chronic encephalopathy with sequelae, spinal cord injury, brain atrophy, cognitive dysfunction, etc., who cannot cooperate with doctors; 3.Patients with incomplete limbs that cannot be tested for HD-sEMG; 4.The duration of treatment in ICU was <7 days; 5.Patients with Clinical data missing.

Design outcomes

Primary

MeasureTime frame
Unilateral biceps brachii and quadriceps HD-sEMG changes;MRC score;APACHE II score;SOFA score;

Countries

China

Contacts

Public ContactXin shaobin

Tianjin People's Hospital

tigerxin2003@aliyun.com+86 131 6407 3828

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026