Preoperative sleep disturbance, After thoracoscopic surgery, and postoperative chronic pain
Conditions
Interventions
Esketamine group:Intraoperative intravenous pumping (0.3mg·kg-1·h-1) of esketamine was continued until the end of surgery
Control group:Constant volume of normal saline was injected intravenously until the end of the operation
Sponsors
The first Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age>=18 years; 2. ASA (American Society of Anesthesiologists) Class I.-III; 3. PSQI score > 5 points one month before surgery; 4. Patients undergoing elective thoracoscopic surgery.
Exclusion criteria
Exclusion criteria: 1.BMI>30kg/m^2; 2. Those who have contraindications to anesthesia or are allergic to narcotic drugs; 3. History of drug abuse; 4. Refusal to sign informed consent; 5. History of thoracic surgery; 6. Cognitive or mental impairment and inability to communicate; 7. Conversion to open surgery; 8. Inability to extubate or be sent to the intensive care unit after surgery; 9. Presence of pain at the surgical site before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of chronic pain ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Abbreviated Injury Scale score;Opioid consumption ;Incidence of adverse reactions ;PSQI score ;Resting NRS score ;Cough NRS score ;Incidence of neuropathic pain;Use of analgesic drugs ; | — |
Countries
China
Contacts
Public ContactJianjun Yang
The first Affiliated Hospital of Zhengzhou University
Outcome results
None listed