Acute cerebral infarction
Conditions
Interventions
Total intravenous anesthesia:Using propofol as the primary anesthetic maintenance agent.
Total inhalation anesthesia group:Using Sevoflurane as the primary anesthetic maintenance agent.
Sponsors
The First Affiliated Hospital of the University of Science and Technology of China,
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. AIS patients who underwent mechanical thrombectomy for the first time after the onset of symptoms; 2. Age>=18 years old; 3. ASA grade III; 4BMI 18.5~24.0 kg/m²; 5. Patients who can understand and cooperate with postoperative follow-up; 6. Occlusion of the proximal intracranial artery of the anterior circulation (carotid artery, middle cerebral artery M1 or M2 or anterior cerebral artery A1 segment) confirmed by computed tomography angiography, magnetic resonance angiography or digital subtraction angiography (DSA).
Exclusion criteria
Exclusion criteria: 1. Abnormal liver, kidney and coagulation function; 2. Patients with preoperative hypoxemia (SpO2 2 before stroke; 6. Computed tomography (CT) scan shows intracranial hemorrhage and impaired consciousness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative MAP and HR;General Information: Age, gender, BMI, ASA classification, comorbidities, duration of surgery, education level, volume of fluid infusion, and dosage of norepinephrine.;Improvement of neurological function after operation;Postoperative Complications;Neurofilament light protein and glial fibrillary acidic protein in venous blood; | — |
Countries
China
Contacts
Public ContactLi Juan
South District, The First Affiliated Hospital of USTC
Outcome results
None listed