periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years old; 2. Patients who will undergo periodontal surgery in the Department of Periodontology, Ninth People's Hospital of Shanghai Jiao Tong University 3. Informed consent of patients
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating patients 2. Patients with systemic diseases accompanied by poor control 3. Known allergy to methylene blue 4. 6-phosphate dehydrogenase deficient individuals 5. Individuals who have used photosensitive drugs in the past 3 months 6. Oral mucosal diseases, tumors, or uncontrolled acute inflammation in the oral cavity 7. Smoking or excessive drinking 8. Mental disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early wound healing progress; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oral Health-related Quality of Life;Postoperative Pain Intensity;Inflammatory cytokines of wound exudate;probing depth;clinical attachment loss;tooth mobility;plaque index;gingiva index;bleeding index; | — |
Countries
China
Contacts
Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine