Esophageal cancer
Conditions
Interventions
Intervention group:1. Esophageal Particle Stent Placement: Following enrollment, comprehensive examinations were conducted to eliminate contraindications. The stent placement procedure was executed un
Sponsors
Affiliated Zhongda Hospital of Southeast University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Esophageal cancer diagnosed and confirmed by pathological histology; (2) Tumor progression after first-line regimen treatment (platinum or 5-fluorouracil based chemotherapy), which was not suitable for resection after MDT discussion. (3) Dysphagia score 3–4 points; (4) ECOG PS score =1.5 × 109 /L; platelets >=80 × 109 /L; albumin >=30 g/L; alanine aminotransferase (ALT), aspartate aminotransferase(AST) =60 mL/min.
Exclusion criteria
Exclusion criteria: (1) dysphagia caused by non-primary esophageal cancer tumors; (2) mild dysphagia with a score of 1 or 2, and non-cooperative dysphagia; (3) lesions with the upper boundary exceeding the level of the seventh cervical vertebra; (4) ulcerative esophageal cancer; (5) history of esophageal stent implantation; (6) concurrent malignancies other than esophageal cancer; (7) presence of severe active autoimmune diseases or a history of autoimmune diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-free survival for dysphagia;Time to Progression, TTP; | — |
Countries
China
Contacts
Public ContactJinhe Guo
Affiliated Zhongda Hospital of Southeast University
Outcome results
None listed