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Efficacy and Safety of Hetrombopag Plus rhIL-11 for Chemotherapy-Induced Thrombocytopenia in Cancer Patients

Efficacy and Safety of Hetrombopag Plus rhIL-11 for Chemotherapy-Induced Thrombocytopenia in Cancer Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098993
Enrollment
Unknown
Registered
2025-03-17
Start date
2025-03-30
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thrombocytopenia after chemotherapy in solid tumors

Interventions

Treatment Group:None
Control Group:None

Sponsors

Affiliated Qingyuan Hospital, Guangzhou Medical University,Qingyuan People's Hospital;
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with tumors admitted to our hospital; 2. Thrombocytopenia after chemotherapy in our hospital, meeting the diagnostic criteria in the "Expert Consensus on Clinical Management of Thrombocytopenia Associated with Tumor Treatment (2021)", and the patient's thrombocytopenia is graded as grade II.~IV.; 3. Age over 18 years with complete clinical data records; 4. Patients who have used hetrombopag ethanolamine tablets in combination with recombinant human interleukin-11 or recombinant human interleukin-11 alone.

Exclusion criteria

Exclusion criteria: 1. Patients with thrombocytopenia not caused by chemotherapy drugs; 2. Patients who have not received chemotherapy in our hospital; 3. Primary hematologic disorders.

Design outcomes

Primary

MeasureTime frame
Gender, age, type of medication, dosage and course of treatment, and length of hospital stay of patients;Laboratory platelet count values before and after medication;Changes in coagulation function;Liver function indexes before and after medication (alanine aminotransferase, aspartate aminotransferase, bilirubin, bile);

Countries

China

Contacts

Public ContactLin Jieru

Qingyuan Hospital Affiliated to Guangzhou Medical University (Qingyuan People's Hospital)

475651333@qq.com+86 763 3113952

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026