Inflammatory bowel disease
Conditions
Interventions
Healthy control group:None
Sponsors
The first affiliated hospital of anhui medical university
Eligibility
Sex/Gender
All
Age
14 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. All the selected patients were in accordance with the Consensus Opinion on the Diagnosis and Treatment of Inflammatory Bowel Diseases proposed by the Chinese Medical Association in 2007 to establish the diagnosis of UC by a combination of clinical, laboratory, imaging, gastrointestinal endoscopy and pathological histology.and healthy people who meet the age criteria.
Exclusion criteria
Exclusion criteria: 1. Age 70 years old 2. BMI 28 kg/m2. 3. Pregnant, breastfeeding and menopausal women. 4. Significant abnormalities in blood indicators (e.g. HB<60G/L, WBC<4.0×10^9/L, PLT<100×10^9/L) and autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. 5. Patients with serious infectious diseases such as hepatitis B, tuberculosis, syphilis and HIV-positive patients. 6. History of gastrointestinal surgery;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spermidine content; | — |
Secondary
| Measure | Time frame |
|---|---|
| lipid peroxidation;ferroptosis-related proteins ACSL4,COX2 and GPX4 expression; | — |
Countries
China
Contacts
Public ContactLu Jian
The first affiliated hospital of anhui medical university
Outcome results
None listed