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The association between hemodynamic changes and prognosis in patients with extracranial and intracranial large arteries atherosclerosis

The association between hemodynamic changes and prognosis in patients with extracranial and intracranial large arteries atherosclerosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098985
Enrollment
Unknown
Registered
2025-03-17
Start date
2021-09-09
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular disease

Interventions

Low WSS:None
High WSS:None

Sponsors

Zhongshan Hospital,Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Age 40-80 years; 2.Extracranial or intracranial large arteries atherosclerosis confirmed by CTA or DSA 3.Patient/Legally Authorized Representative has signed the Informed Consent form

Exclusion criteria

Exclusion criteria: 1.The degree of stenosis in bilateral anterior circulation arteries was >=50% 2. The degree of stenosis in postterior circulation arteries was >=50% 3. Athrosclerosis caused by dissection, arteritis, abnormal coagulation function, hereditary disease 4. Coexisting high risk factors for cardiogenic stroke 5.Evidence of intracranial arterial aneurysm (>10 mm), moyamoya disease, arteriovenous malformation, or intracranial tumor (except asymptomatic meningioma); 6.Severe heart/renal/liver dysfunction 7.Anticipated life expectancy < 1 year; 8.MRI contraindication 9.Any other condition that poses a significant hazard to the subject if mechanical thrombectomy is in the opinion of the investigator

Design outcomes

Primary

MeasureTime frame
Stroke reccurence;

Secondary

MeasureTime frame
Vascular death event;Changes in neuropsychological cognitive function;

Countries

China

Contacts

Public ContactJing Ding

Zhongshan Hospital,Fudan University

ding.jing@zs-hospital.sh.cn+86 21 6404 1990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026