Burn scar
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18-60 years old, regardless of gender; 2. History of burn scar, scar area = 1% of total body surface area (TBSA); 3. There are no infectious wound around the scar; 4. The subjects are fully informed, voluntarily signe the informed consent, and are able to complete the trial in accordance with the requirements of the protocol.
Exclusion criteria
Exclusion criteria: 1. Patients with schizophrenia, bipolar disorder, organic mental disorder, or cognitive impairment; 2. Patients with a history of psychological disorders prior to burns; 3. Patients with clear and severe functional impairments in organs such as the heart, brain, liver, and kidneys; 4. Patients with psoriasis, immunodeficiency diseases, chronic skin or connective tissue diseases; 5. Patients with a history of drug abuse; 6. Patients with scar constitution; 7. Those enrolled in other clinical trials within 3 months before screening; 8. Patients with cancer and malignant tumors; 9. Pregnant or lactating women; 10. Thoes who are not suitable to participate in the research according to the judgment of the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Vancouver Scar Scale (VSS) assesses patients for scar status;The Patient and Observer Scar Assessment Scale (POSAS) assesses patient scar status;Scar thickness measured by ultrasound;Blood perfusion measured by laser Doppler flowmetry;Hospital anxiety and depression scale;Rosenberg self esteem scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Transcriptome sequencing result; | — |
Countries
China
Contacts
The First Affiliated Hospital of the Air Force Medical University