Gynecological patients with single hole laparoscopy
Conditions
Interventions
Ketorolac tromethamine group:Ketorolac tromethamine 60mg+0.25% ropivacaine hydrochloride injection mixture 40ml.
Dexamethasone group:Dexamethasone 10mg+0.25% ropivacaine hydrochloride injection mixture 40ml.
Control group:0.25% ropivacaine hydrochloride 40ml
Sponsors
Zigong Maternal and Child Health Care Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Gynecological single hole laparoscopic surgery; 2. Aged 18-65 years; 3. American Society of Anesthesiologists (ASA) classification I-III.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of allergy to local anesthetics; 2. Patients with a history of allergy to ketorolac tromethamine and aspirin or other non-steroidal anti-inflammatory drugs; 3. Patients with active peptic ulcer, recent gastrointestinal bleeding or perforation, and with a history of peptic ulcer or gastrointestinal bleeding; 4. Patients with renal failure caused by renal function injury and insufficient blood volume; 5. Patients with suspected or diagnosed cerebrovascular hemorrhage, bleeding tendency, incomplete hemostasis and high-risk hemorrhage; 6. Patients with a history of allergy to dexamethasone.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of moderate to severe pain in 24 hours ; | — |
Secondary
| Measure | Time frame |
|---|---|
| BCS comfort score within 48 hours after surgery;Consumption of analgesic drugs and analgesia rescue rate;QoR-15 scale evaluation ;Incidence of postoperative nausea and vomiting;Perioperative blood glucose changes; | — |
Countries
China
Contacts
Public ContactLina Wang
Zigong Maternal and Child Health Care Hospital
Outcome results
None listed