Heart Failure
Conditions
Interventions
Sponsors
Nanyang Second General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of coronary heart disease and heart failure in Western medicine: Have a history of coronary heart disease leading to heart failure or risk factors for coronary heart disease; Have obvious signs or symptoms of heart failure; NYHA cardiac function classification belongs to grade II-IV. Left ventricular ejection fraction (LVEF) =450 pg/mL. (2) Complying with the TCM syndrome differentiation standard of Yang deficiency and blood stasis. (3) Aged from 18 to 80 (including boundary value). (4) Grade II to IV (NYHA cardiac functional classification). (5) Good mental state able to communicate barrier-free. (6) Informed consent signed.
Exclusion criteria
Exclusion criteria: (1) Heart failure caused by liver-kidney and other important organ. (2) Women who are pregnant and lactating, people with mental disorders and those who are unwilling to cooperate. (3) Patients with severe liver and kidney dysfunction, electrolyte disorders and serious primary diseases of the endocrine system, hematopoietic system etc. (4) Patients with combined shock, severe arrhythmia, complete atrioventricular block, obstructive cardiomyopathy, unrepaired valvular disease, constrictive pericarditis, pulmonary embolism, implanted cardiac pacemakers and other ventricular assist devices, obvious infection and uncontrolled hypertension. (5) Those who have a clear history of allergy to the drugs used in this study. (6) Those who have participated in other clinical trials within 3 months. (7) Those who cannot perform the 6-minute walk test due to limb disability or other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Minnesota Heart Failure Quality of Life Questionnaire;NYHA cardiac function grading;Traditional Chinese Medicine,TCM syndrome integration; | — |
Secondary
| Measure | Time frame |
|---|---|
| NT-proBNP;6-minute walking distance;Related parameters measured by cardiac ultrasound;Long term prognosis; | — |
Countries
China
Contacts
Public ContactLv Shuzhi
Nanyang Second General Hospital
Outcome results
None listed