none
Conditions
Interventions
Sponsors
Fuzhou University Affiliated Provincial Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 65-80 years; 2. Able to walk independently without aids; 3. Capable of communicating and cooperating with questionnaires, assessments, and MRI scans; 4. Willing to participate and sign an informed consent form; 5. Not enrolled in other clinical studies.
Exclusion criteria
Exclusion criteria: 1. Neurological deficits (e.g., visual/hearing impairments) 2. Advanced, severe, or unstable comorbidities (e.g., severe primary cardiac, hepatic, or renal diseases) 3. Neurological or psychiatric disorders (e.g., stroke, epilepsy) 4. Diseases causing cerebral dysfunction 5. Metal implants (e.g., fixed metallic dentures, pacemakers) or other contraindications to MRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting-State Functional Magnetic Resonance Imaging (rs-fMRI);Postural Stability;Fried Frailty Phenotype; | — |
Secondary
| Measure | Time frame |
|---|---|
| Timed Up-and-Go test;Short Physical Performance Battery;Berg Balance Scale;Mini Nutritional Assessment Short-Form;five - item Geriatric Depression Scale;Insomnia Severity Index;Modified Falls Scale; | — |
Countries
China
Contacts
Public ContactLin Zhonghua
Fuzhou University Affiliated Provincial Hospital
Outcome results
None listed