Periprosthetic fracture after hip replacement surgery
Conditions
Interventions
Acute isovolumetric blood dilution group:After stable anesthesia induction, blood was drawn from the internal jugular vein (at a rate of 20ml/min) and stored in a blood collection bag containing sodiu
Intraoperative blood recovery group:This study used a Jingjing 3000P blood recovery machine to recover surgical bleeding. Anticoagulants were added to 500ml of compound sodium chloride solution with 2
Acute isovolumetric blood dilution combined with intraoperative blood recovery group:After stable anesthesia induction, blood wa
Sponsors
Xi'an Honghui Hospital Affiliated to Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists (ASA) score I-II; 2. Preoperative hemoglobin >= 110g/L, hematocrit >= 35%, platelet count >= 100 × 10^9/L; 3. Expected intraoperative bleeding>500ml; 4. Normal coagulation function, normal heart, lung, liver, and kidney function, and no history of taking anticoagulant drugs; 5. The patient signs an informed consent form for anesthesia.
Exclusion criteria
Exclusion criteria: 1. Individuals with contraindications to general anesthesia or a history of anesthesia accidents; 2. Hemoglobin<100g/L, hypoalbuminemia, platelet and coagulation dysfunction; 3. Patients with combined traumatic brain injury, intracranial hypertension, stroke, unstable angina, and myocardial infarction; 4. Respiratory dysfunction, obstructive pulmonary disease, presence of difficult airways, or difficulty in endotracheal intubation (modified Mahalanobis score III or IV); 5. Uncontrolled diabetes or hypertension; 6. Severe liver dysfunction or severe renal insufficiency; 7. History of alcoholism or drug dependence; 8. Abuse or long-term use of anesthetics, sedatives, and analgesics; 9. Individuals with a history of mental illness; 10. Pregnant and lactating women; Women or men with fertility are unwilling to use contraception throughout the entire trial period; Subjects with pregnancy plans within one month after the trial (including male subjects); 11. The researchers believe that there are any other factors that are not suitable for participants in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| heart rate;mean arterial pressure;central venous pressure;Hemoglobin concentration;prothrombin time;activated partial thromboplastin time; | — |
Secondary
| Measure | Time frame |
|---|---|
| hematocrit;Intraoperative blood loss;Postoperative infection;Postoperative hospitalization time; | — |
Countries
China
Contacts
Public ContactGuang Yang
Anesthesia Department of Xi'an Red Cross Hospital Affiliated to Xi'an Jiaotong University
Outcome results
None listed