Pulmonary fragility
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA classification is I-III level 2. Age >= 65 years old, gender not limited 3. Elective thoracoscopic lung resection surgery with an estimated surgery time of 1-4 hours 4. Expected survival period>12 months 5. Conduct ethical review and sign informed consent form
Exclusion criteria
Exclusion criteria: 1. Emergency surgery 2. Patients with severe heart, liver, and kidney dysfunction combined 3. MMSE score<24 points 4. Alcohol or drug dependence Have undergone thoracic surgery or cranial surgery within 5.1 years 6. History of central nervous system disease or delirium occurring within 2 weeks prior to surgery 7. Participated in other relevant clinical studies within 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Memory Delirium Assessment Scale;The 3-Minute Diagnostic Confusion Assessment Method;Mini-Mental State Examination;Assessment of lung fragility status;Neurofilament Light Chain;Lipocalin 2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative information collection;Intraoperative vital signs; | — |
Countries
China
Contacts
Department of Anesthesiology, Qingdao Municipal Hospital