disorders of consciousness
Conditions
Interventions
Auditory stimulation group:Auditory stimulus: Play the school bell tone for 30 seconds, followed by a 30-second interval
play percussion music for 3 minutes, with a 30-second interval
play family recordings and electronic synthesized sounds, each repeated twice.
Visual Stimulation Group:Visual stimulus: Alternate the display of the patients own photo and another person's photo, each lasting for 15 seconds, for a total of 3 minutes.
The group exposed to taste and smell stimulation:Olfactory and gustatory stimulus:
- Olfactory stimulus: Smell the aroma of wine or vinegar, changing every minute, for a total of 5 minutes, with venti
The group subjected to tactile pain stimulus:Tactile pain stimulus:
- Pain stimulus: Lightly prick each of 20 areas once, with an interval of 5 seconds
deep tactile stimulus: Knock on each of 14 joints once, with an interval of 5 seconds.
Sponsors
The Fourth Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 80 years old; 2.Glasgow Coma Scale (GCS) score at admission was less than 8 points; 3.Caused by traumatic brain injury (TBI), stroke or hypoxia, with a duration exceeding 28 days; 4. Duration of consciousness disorder (including coma, vegetative state, and minimally conscious state) was more than 2 weeks; 5.Stable vital signs, without significant organ failure; 6.Able to obtain informed consent from the caregiver.
Exclusion criteria
Exclusion criteria: 1.History of epilepsy, mental or neurological diseases; 2.Long - term use of sedative or anti - epileptic drugs; 3.Patients who fail to complete the two - week treatment course; 4.Patients who terminate treatment due to severe complications during the treatment process.; 5.Patients who drop out naturally (including transfer to another hospital, transfer to another department, refusal of treatment by family members midway, death); 6.Uncontrollable infections or other serious medical conditions; 7.Inability to obtain informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Near infrared detection; | — |
Secondary
| Measure | Time frame |
|---|---|
| CRS-R scale assessment;glassgow assessment; | — |
Countries
China
Contacts
Public ContactZhang Juan; Su Min
Suzhou Traditional Chinese Medicine Hospital, The Fourth Affiliated Hospital of Soochow University
Outcome results
None listed