cognitive dysfunction in maintenance hemodialysis patients
Conditions
Interventions
Resistance exercise intervention group:Blood dialysis 3 times a week+resistance exercise during dialysis 3 times a week,
Dialysis for 4 hours each time, resistance exercise for about 30 minutes per se
control group:Blood dialysis 3 times a week, 4 hours each time
Sponsors
Blood Purification Center of Nephrology Department of PLA Army Characteristic Medical Center
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. MHD patients aged >= 18 years old; 2. Regular hemodialysis treatment for >= 3 months, dialysis 3 times/week, dialysis 4 hours/time; 3. No leg joint muscle movement disorders; 4. Clear consciousness, no verbal communication barriers, no listening, speaking, or writing barriers; 5. The condition is stable, with heart function levels I-II, and no chest tightness, chest pain, or sitting breathing during rest; 6. Patients who voluntarily participate in this study.
Exclusion criteria
Exclusion criteria: 1.Poor blood pressure control (systolic blood pressure >= 160 mmHg or diastolic blood pressure >= 100 mmHg); 2. Patients with consciousness disorders and mental illnesses; 3. Combined acute cardiovascular and cerebrovascular events: angina pectoris, myocardial infarction, malignant arrhythmia, cerebral infarction, etc And cerebral hemorrhage, etc; 4.Severe respiratory distress requires continuous oxygen inhalation during dialysis; 5. Patients with severe thrombophlebitis, renal osteodystrophy, acute thrombosis of the lower limbs, severe swelling of the muscles or joints of the lower limbs, limb mobility disorders, and intolerance of exercise; 6 Combining severe infections, surgery, and trauma; 7. Patients with combined tumors and severe cachexia; 8. Individuals with visual or hearing impairments; 9. Pregnant or lactating women; 10. Preparing for kidney transplant surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MoCA-B Scale rating; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dialysis adequacy assessment includes spKt/V, URR;Inflammation assessment includes CRP, IL-6;Analysis of human body composition;nutritional status assessment;Physical function assessment includes a 6-minute walk test and 10 sit stand tests; 22/10000 22/10000 real-time translation Pittsburgh Sleep Quality Index (PSQI) assessment Pittsburgh Sleep Quality Index (PSQI) assessment;Evaluation of Kidne Disease Quality of Life Scale (KDQOL-36TM1.3);Dialysis adequacy assessment —— URR;Inflammation assessment—IL-6;Physical function assessment ——10 sit stand tests; | — |
Countries
China
Contacts
Public ContactLiu Jun
PLA Army Characteristic Medical Center
Outcome results
None listed