Postoperative Hypoxemia
Conditions
Interventions
Intervention group:Continuous High-Frequency Oscillation
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. age >= 18 years; 2. Patients with postoperative hypoxemia admitted to the ICU (defined as SpO2 < 90% for more than 10 seconds, or PaO2/FiO2 < 300 mmHg);
Exclusion criteria
Exclusion criteria: 1. untreated pneumothorax or massive pleural effusion; 2. Severe hemodynamic instability; 3. pregnancy; 4. Recent chest trauma or burns; 5. Contraindications for EIT (e.g., chest drainage tubes, cardiac pacemakers or implantable defibrillators, neck implants) or ultrasound; 6. For patients with relative contraindications to CHFO (e.g., history of pneumothorax, recent pneumonectomy, pulmonary hemorrhage, myocardial infarction, vomiting), inclusion will be discussed and determined by the clinicians;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| End-expiratory lung impedance (EELI), tidal impedance variation (TIV);Modified Lung UltrasoundScore(mLUS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Coefficient of Variation (CV);Global Inhomogeneity(GI);P/F, pH, PaCO2; | — |
Countries
China
Contacts
Public ContactHongping Qu
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed