cerebral palsy
Conditions
Interventions
Intervention group:exercise therapy and repetitive transcranial magnetic stimulation
Sponsors
Shenzhen Children’s Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. In line with the definition of cerebral palsy formulated in the "Chinese Guidelines for the Rehabilitation of Cerebral Palsy (2022)", the medical diagnosis is spastic hemiplegia; 2. age 2-6 years old, gender is not limited; 3. The ability to understand and comply with the instructions of the therapist; 4. The childUnilateral muscle tone of the lower extremities increased, and the MAS rating was >=1; 5.The Gross motor function classification system (GMFCS) was rated as Grade I-III; 6. The families of the children had informed consent for this study and signed relevant documents.
Exclusion criteria
Exclusion criteria: 1.Patients with severe comorbidities (complete or partial blindness, lower limb deformities); 2.Severe neurological diseases and underlying conditions such as infections, coagulation dysfunction, respiratory, kidney, and cardiac dysfunction; 3.Patients with a history of epilepsy; 4.Patients with metal implants; 5.Patients who have received chemical denervation injections, such as BTX-A, intrathecal baclofen, phenol, ethanol block, and surgeries related to lower limb motor function and muscle tone, including selective posterior roototomy, within six months prior to participating in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ALFF(Amplitude of Low Frequency Fluctuation); | — |
Secondary
| Measure | Time frame |
|---|---|
| FC (Functional Connectivity);FA (fractional anisotropy);GMFM-88(Gross Motor Function Measure 88);FMA(Fugl-Meyer assessment scale);Muscle tone assessment;10WMT(10 Meter Walk Test);gait;MEP(Motor-evoked Potential);iEMG,EMG integral value;RMS,Square root amplitude; | — |
Countries
China
Contacts
Public ContactZhang Yiwen
Shenzhen Children’s Hospital
Outcome results
None listed