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Research on the effect and mechanism of prefrontal rTMS in improving ankle function in patients with lateral ankle sprain

Research on the effect and mechanism of prefrontal rTMS in improving ankle function in patients with lateral ankle sprain

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098840
Enrollment
Unknown
Registered
2025-03-14
Start date
2025-01-16
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lateral ankle sprain

Interventions

Prefrontal rTMS group:Repetitive Transcranial Magnetic Stimulation (rTMS)
Pseudo-excitation group:Pseudo-excitation

Sponsors

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: The research subjects should meet the following criteria: 1. Have a history of a typical lateral ankle sprain, with confirmed injury to the lateral collateral ligament of the ankle by MRI and resulting in pain and ankle movement disorders; 2. The time from the most recent sprain to the examination is >= 2 weeks; 3. The patient has stable vital signs, is conscious, and cooperates with the examination and treatment; 4. Age 18-80 years old, gender; 5. The patient or guardian agrees to sign the informed consent form.

Exclusion criteria

Exclusion criteria: Objects that meet any of the following criteria will be excluded from this study: 1. Patients with reduced or failed function of important organs such as the heart, lungs, liver, and kidneys, or those with malignant tumors; 2. Patients with a history of surgery on other ankle bone and muscle structures (including bones, ligaments, and/or nerves) except for lateral ligament repair or reconstruction; 3. Patients with a history of ankle fractures; 4. Patients who, after assessment by a physician, need surgical treatment due to poor mechanical stability of the ankle joint; 5. Patients who have had epileptic seizures in the past three months or are currently taking antiepileptic drugs; 6. Patients with pacemakers or other implanted electrodes; 7. Patients with skull defects.

Design outcomes

Primary

MeasureTime frame
AOFAS Score;

Countries

China

Contacts

Public ContactXie Qing

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

ruijin_xq@163.com+86 136 7157 5851

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026