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Effect of the implementation of clinical practice guidelines for postoperative pain management in adults on postoperative pain in patients: a multicenter, stepwise cluster randomized trial protocol

Effect of the implementation of clinical practice guidelines for postoperative pain management in adults on postoperative pain in patients: a multicenter, stepwise cluster randomized trial protocol

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098836
Enrollment
Unknown
Registered
2025-03-14
Start date
2025-03-20
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute pain

Interventions

Intervention group:Cluster pain management measures were formed according to the recommendations of clinical practice guidelines for postoperative pain management in adults.
Control group:Pain management strategies before implementing guideline recommendations.

Sponsors

Zhengzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Hospitals are qualified to implement the recommendations of the guidelines; 2.Patients undergoing elective surgery requiring postoperative analgesia; 3.Age>=18 years old; 4.ASA grade 1-4; 5.Patients agreed to participate in the investigation and evaluation of postoperative pain related results.

Exclusion criteria

Exclusion criteria: 1.The hospitalization time of patients was less than 48 hours, and the follow-up could not be completed; 2.The patient could not be followed up because of impaired consciousness and cognitive status. 3.Patients who needed to be transferred to ICU for postoperative analgesia management; 4.Patients undergoing obstetric surgery.

Design outcomes

Primary

MeasureTime frame
Incidence of moderate to severe postoperative pain in surgical patients before and after the implementation of the guideline;

Secondary

MeasureTime frame
Utilization rate of recommendations for the 17 clinical questions of the guideline by health care providers;NRS scores at rest at 6 h, 12 h, 24 h and 48 h after surgery ;NRS scores at movement at 6 h, 12 h, 24 h and 48 h after surgery ;The cumulative opioid consumption of patients within 48 hours after surgery;The Brief pain assessment (BPI) score at 24 h and 48 h after operation;The QoR-15 scale before operation and 24 h and 48 h after operation;Resting-sedation scale (RASS) at 6 h and 12 h after operation;Patient satisfaction with analgesia;Incidence of nausea and vomiting;Incidence of Respiratory Depression;Incidence of pruritus;Incidence of urinary retention;Incidence of Delirium;The incidence of complications of analgesic procedures (nerve block or intraspinal analgesia);LOS(length of stay);Total cost of hospitalization;

Countries

China

Contacts

Public ContactYan Wang

Zhengzhou Central Hospital

wangy0377@126.com+86 135 0371 4779

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026