Skin whitening
Conditions
Interventions
Test side:The treatment equipment was PicoWell Pro picosecond Nd:YAG laser therapy instrument (Peninsula Medical, China) with wavelength of 1064 nm, pulse width of 250 ps, spot size of 8 ~ 10 mm, freq
Control side:The treatment equipment was M22 intense pulsed light (Lumenis Limited, USA), filter 560 nm (type III), 590 nm (type IV-V), spot size 15 mm×35 mm, double pulse, pulse width 3.0 ~ 5.0 ms, e
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Age 18 to 60 years old, gender unrestricted, those who require facial skin whitening; 2.Fitzpatrick skin types III to V; 3.Voluntary participation and signing of the informed consent form. 4.Good compliance and willingness to cooperate with follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with facial inflammation, infection, ulceration or other skin diseases, including chloasma, nevus fusco-coccineus, seborrheic keratosis, etc. 2. Patients who have undergone laser, radiofrequency, chemical peeling, botulinum toxin injection, etc. within the past six months. 3. Patients who have been exposed to intense sunlight or undergone sunbathing within the past month. 4. Patients who are photosensitive or are currently using photosensitive drugs (oral or topical). 5. Patients with systemic diseases, immune deficiency diseases or using immunosuppressants, as well as those with mental illness. 6. Pregnant or lactating women. 7. Patients with keloid-prone skin or keloids. 8. Patients who refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physician’s Global Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| VISIA absolute score;Noninvasive skin physiological index; | — |
Countries
China
Contacts
Public ContactXiang Wen
West China Hospital, Sichuan University
Outcome results
None listed