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Immediate Effects of Transcranial Alternating Current Stimulation on Upper Limb Motor Function After Stroke: A Randomized Controlled Trial

Immediate Effects of Transcranial Alternating Current Stimulation on Upper Limb Motor Function After Stroke: A Randomized Controlled Clinical Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098817
Enrollment
Unknown
Registered
2025-03-13
Start date
2025-04-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Confirmed as ischemic/hemorrhagic stroke by CT/MRI; 2. Age: no less than 45 years old and no more than 80 years old. Gender is not limited. 3. Primary school education or above; 4. Initial onset, disease course >= 3 months and 20 points; High school education or above > 24 points; 6. Unilateral upper limb motor dysfunction, Brunnstrom stage >= II; 7. Right-handed; 8. Participate voluntarily and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Those with unstable vital signs in the acute phase; 2. Those who are unable to communicate with others normally such as aphasia and hearing impairment; 3. Patients with severe bone, joint and muscle diseases; 4. Pregnant or lactating women; 5. Severe organ diseases and severe mental diseases, including but not limited to the following diseases: heart diseases (such as myocardial infarction, atrial fibrillation), liver diseases (such as liver failure, liver cancer), kidney diseases (such as end-stage renal disease), lung diseases (such as respiratory failure), mental diseases (such as schizophrenia); 6. Contraindications to transcranial alternating current stimulation (tACS) and electroencephalography (EEG), such as pacemaker, cardiac stent, claustrophobia, head trauma or skull defect, scalp infection, wounds, etc.; 7. Patients with a history of epilepsy; 8. Participated in or are participating in other clinical projects one month before enrollment.

Design outcomes

Primary

MeasureTime frame
EEG electrode level outcomes;EEG connectivity level outcomes;EEG network level outcomes;

Countries

China

Contacts

Public ContactXue Xin

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

xuexin@shutcm.edu.cn+86 152 0215 1580

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026