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Effect of different administration methods of dexamethasone on postoperative pain and swelling following implant flap surgery: A randomized controlled trial of patient-centered outcomes

Effect of different administration methods of dexamethasone on postoperative pain and swelling following implant flap surgery: A randomized controlled trial of patient-centered outcomes

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098816
Enrollment
Unknown
Registered
2025-03-13
Start date
2024-01-01
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentition defect

Interventions

The postoperative oral dexamethasone group:Postoperative oral dexamethasone
The intraoperative submucosal injection dexamethasone group:Intraoperative submucosal injection of dexamethasone

Sponsors

Affiliated Stomatological Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Patients aged 18~65 with dentition defects, and those who have no continuous tooth loss in the same quadrant in the mouth, and there is no special requirement for gender; (2) The patient has good compliance, is informed and agrees to participate in this study; (3) No systemic diseases or bone metabolism diseases, no other oral and facial diseases such as chronic minor sinusitis, history of parotid gland surgery, etc.; (4) tolerate implant surgery; (5) Denial of dexamethasone allergy.

Exclusion criteria

Exclusion criteria: (1) Patients with systemic diseases, such as diabetes mellitus or osteoporosis or inflammatory bowel disease; (2) Patients with active infection or inflammation in the implant area, or obvious apical inflammation of adjacent teeth; (3) History of head and neck radiotherapy; (4) Patients with insufficient available bone mass and need to undergo bone augmentation operation; (5) Those who have taken glucocorticoids in the past 6 months.

Design outcomes

Primary

MeasureTime frame
Pain level;Swelling score;

Secondary

MeasureTime frame
Duration of surgery;Number of implants;

Countries

China

Contacts

Public ContactHe Feng

Affiliated Stomatological Hospital of Nanjing Medical University

hefeng881@aliyun.com+86 180 5108 2829

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026