Diseases related to premature infants
Conditions
Interventions
NIV group:NA
Mechanical ventilation group:NA
Conventional oxygen therapy group (nasal cannula, hood oxygen therapy, incubator oxygen therapy):NA
Non-oxygenation group:NA
Sponsors
Wenling Maternal and Child Health Care Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The guardians of premature infants have sufficient reading comprehension ability and sign the informed consent form. 2. Premature infants with a gestational age of less than 37 weeks. 3. Premature infants who have used antibiotics for less than 5 days.
Exclusion criteria
Exclusion criteria: 1. Severe congenital diseases, including congenital heart disease, digestive tract malformations, and inherited metabolic disorders; 2. Chromosomal abnormalities. 3. Newborns who died without emergency treatment upon admission or died within a few hours despite active rescue and treatment. 4. Newborns who were discharged automatically with a hospitalization period of less than one week. 5. Incomplete clinical data. 6. Families who did not agree to participate and withdrew halfway. 7. Use of probiotics. 8. Use of antibiotics for more than 5 days. 9. Mothers with immune system or severe infectious diseases and a history of using immunosuppressants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora structure;Follow-up assessment items: General conditions, such as feeding status, medical history during the follow-up period, weight, height, head circumference, chest circumference, vision, blood routine, trace elements, etc.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical data: Information such as gender, gestational age, birth weight, age, mode of delivery, Apgar score, maternal gravidity and parity, maternal pregnancy complications, amniotic fluid status, placental status, resuscitation measures received, and antibiotic usage, as well as the disease conditions in preterm infants.;Neuropsychological development assessment items, such as General Movements Assessment (GMS) , Alberta Infant Motor Scale (AIMS) , and Griffiths Scales of Child Development for detection.; | — |
Countries
China
Contacts
Public ContactEnfu Tao/Haiting Li
Wenling Maternal and Child Health Care Hospital
Outcome results
None listed