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Effect of different anesthesia modalities on tourniquet myocardial injury in patients undergoing orthopedic surgery

Effect of different anesthesia modalities on tourniquet myocardial injury in patients undergoing orthopedic surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098795
Enrollment
Unknown
Registered
2025-03-13
Start date
2024-04-10
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tourniquet reaction

Interventions

General anesthesia group (group P):general anesthesia
Combined spinal-epidural anesthesia group(groupC):Combined spinal-epidural anesthesia

Sponsors

The First Affiliated Hospital of Gannan Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients who underwent lower limb surgery (tibia, fibula, calcaneus fracture or knee arthroscopy) with tourniquet; 2. ASA grade I.-III; 3. No serious underlying diseases or dysfunction of vital organs; 4. Age>=50; 5. Informed consent is obtained

Exclusion criteria

Exclusion criteria: 1. The patient is allergic to any of the narcotic drugs required for the experiment or has contraindications to the use of such drugs; 2. Those with mental illness or communication disorders; 3. Patients with a history of long-term use of sedative and analgesic drugs in the past; 4. Patients with severe dysfunction of important organs, such as heart, lungs, liver, kidneys, etc.; 5. Those with contraindications to neuraxial anesthesia.

Design outcomes

Primary

MeasureTime frame
Incidence of myocardial injury;

Secondary

MeasureTime frame
Duration of tourniquet use;Incidence of tourniquet reactions;Hemodynamic indexes;

Countries

China

Contacts

Public ContactMaolin Zhong

The First Affiliated Hospital of Gannan Medical University

zml8802@163.com+86 136 0797 8802

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026