Allergic rhinitis
Conditions
Interventions
Control group:Oral placebo
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
4 Years to 12 Years
Inclusion criteria
Inclusion criteria: (1) Children with allergic rhinitis aged 4-12 years, who meet the diagnostic criteria for allergic rhinitis and whose main allergens are dust mites and animal dander; (2) Have not received probiotic drugs or immune modulators within 3 months prior to treatment; (3) Complete clinical data.
Exclusion criteria
Exclusion criteria: (1) Individuals with important organ dysfunction; (2) Patients with combined malignant tumors; (3) Individuals with coagulation system, immune system, and cardiovascular diseases; (4) Patients with combined asthma and other respiratory and gastrointestinal diseases; (5) Drug allergy patients in this study; (6) Merge severely infected individuals; (7) Individuals with severe mental illnesses; (8) Long term use of antibiotics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TNSS - Total Nasal Symptom Score;Nasal mucosal cytokines; | — |
Secondary
| Measure | Time frame |
|---|---|
| RQLQ - Rhinoconjunctivitis Quality of Life Questionnaire;Bristol Stool Form Scale;Gastrointestinal Symptom Rating Scale, GSRS;Intestinal flora;Cytokines in feces; | — |
Countries
China
Contacts
Public ContactZhang Jinping
Shanghai Sixth People's Hospital
Outcome results
None listed