painless gastroscopy
Conditions
Interventions
Afentanil group (Group A):10ug/kg afentanil +0.15-0.2ml/kg EP mixture (etomidate 20mg and 1% propofol 200mg
Osselidine Group (Group O):0.03mg/kg oxelidine +0.15-0.2ml/kg EP mixture (etomidate 20mg and 1% propofol 200mg)
Sufentanil group (S group):0.1ug/kg Sufentanil +0.15-0.2ml/kg EP mixture (etomidate 20mg, 1% propofol 200mg)
Sponsors
Yanting County People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients who intend to undergo painless gastroscopy and voluntarily participate in the study and sign the informed consent form, aged 18-60 years, with a BMI of 18-28 kg/m², and ASA grade I or II.
Exclusion criteria
Exclusion criteria: 1. Those who have cognitive dysfunction in the past, suffer from mental illness, and have communication difficulties; 2. Those with a history of alcohol or drug abuse; 3. Those who use anesthetic drugs, sedatives or opioids 24 hours before surgery; 4. Those who have participated in any clinical trial as a subject within 3 months before selection; 5. Those who are allergic or hypersensitive to the drugs used in the study; 6. Pregnant or lactating women or patients with birth plans within 3 months; 7. Patients with symptoms of acute upper gastrointestinal bleeding or need gastroscopy treatment; 8. Patients who require complex endoscopic techniques for diagnosis and treatment; 9. Those who intend to undergo tracheal intubation; 10. People who are judged to have difficulty in respiratory tract management.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory circulatory index;Total amount of propofol used;The interval between the start of administration and the disappearance of eyelash reflexes;The interval between discontinuation of administration and instruction to open eyes after surgery;The interval between withdrawal and discharge;Patient's sedation level at 5-minute intervals within 20 minutes of discontinuation;Incidence of nausea and vomiting;All adverse reactions occurred during and after surgery; | — |
Countries
China
Contacts
Public ContactJiayan Luo
Yanting County People's Hospital
Outcome results
None listed