indirect inguinal hernia
Conditions
Interventions
Age group: 3-6 years:Initial dose of ciprofol: 0.6 mg/kg.
Age group: 7-12 years:Initial dose of ciprofol: 0.6 mg/kg.
Sponsors
The Second Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 3 to 12 years. 2.Body mass index (BMI) ranges: 13.6-18.2 kg/m^2 for ages 3-4 years, 14.0-19.3 kg/m² for ages 5-7 years, 14.7-20.4 kg/m^2 for ages 8-10 years, and 15.4-22.4 kg/m^2 for ages 11-12 years. 3.American Society of Anesthesiologists (ASA) physical status classification I-II. 4.Normal developmental status. 5.Informed consent was obtained from the legal guardians of the children prior to anesthesia.
Exclusion criteria
Exclusion criteria: 1.Allergy to ciprofol or propofol. 2.Confirmed difficult airway. 3.Ongoing sedative therapy (e.g., propofol, morphine, fentanyl, sufentanil, midazolam, dexmedetomidine, ketamine) or recent use of sedatives (withdrawal time <24 hours). 4.Cardiac or respiratory diseases. 5.Hepatic or renal dysfunction. 6.Developmental malformations or delays. 7.If any of the above answers is "No," the subject is excluded from participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ED50 and ED95 of ciprofol for suppressing the tracheal intubation response; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse effects;Systolic Blood Pressure (SBP);Diastolic Blood Pressure (DBP);Heart Rate (HR);Respiratory Rate (RR);Onset Time of Sedation; | — |
Countries
China
Contacts
Public ContactRuifeng Zeng
Department of Anesthesiology, The 2nd Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed