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Remimazolam alleviates ED90 in children of different ages with preoperative anxiety

Remimazolam alleviates ED90 in children of different ages with preoperative anxiety

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098747
Enrollment
Unknown
Registered
2025-03-13
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Young age group:Intravenous injection of remimazolam 0.2mg/kg as the statring dose
Elderly group:Intravenous injection of remimazolam 0.2mg/kg as the statring dose

Sponsors

Third Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1.Children undergoing elective general anesthesia surgery 2. ASA grade I or II,; 3. age 1~6 years; 4. gender is not limited,; 5. body mass index is 13~20kg/m²,. 5. PSAS score > 3.

Exclusion criteria

Exclusion criteria: 1. Children with upper respiratory tract infection in the past 2 weeks; 2. Anemia, malnutrition, abnormal liver and kidney function; 3.Severe cardiovascular disease; Persons with intellectual disabilities; 4.Have neuropsychiatric disorders; History of allergy to narcotic drugs; 5.History of taking sedative-hypnotic drugs

Design outcomes

Primary

MeasureTime frame
90% effective dose;

Secondary

MeasureTime frame
Mean arterial pressure;Heart rate;Adverse reactions during sedation;

Countries

China

Contacts

Public ContactZhu Xuming

Third Affiliated Hospital of Zhengzhou University

zhuxuming6688@126.com+86 155 3713 1820

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 21, 2026